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软肝化纤丸治疗慢性乙型肝炎合并早期肝硬化40例临床分析
软肝化纤丸治疗慢性乙型肝炎合并早期肝硬化40例临床分析
作者:张金平 陈…    教学科研来源:中国现代实用医学杂志    点击数:    更新时间:2007-1-18
  【摘要】目的 探讨软肝化纤丸治疗慢性乙型肝炎(CHB)合并早期肝硬化患者的临床疗效。方法 将慢性乙型肝炎合并早期肝硬化患者81例随机分为治疗组(40例)与对照组(41例)。治疗组给予软肝化纤丸治疗;对照组用鳖甲软肝片、利加隆(水飞蓟素胶囊),疗程3个月。观察治疗前后肝功(ALT、AST、ALB、TBiL)和肝纤维化(HA、IV-C、LN)等指标的变化情况。结果 疗程结束后,治疗组患脾大、门静脉增宽、肝纤维化指标明显好转,与对照组比较差异有显著性(P<0.05或P<0.01)。结论 软肝化纤丸治疗慢性乙型肝炎合并早期肝硬化疗效优于鳖甲软肝片,利加隆。
    【关键词】乙型肝炎 肝纤维化 早期肝硬化 软肝化纤丸 鳖甲软肝片 利加隆
    【Abstract】Objective The goal discusses the soft liver chemical fiber pill treatment chronic hepatitis B (CHB)Merge early time liver cirrhosis patient's clinical curative effect. Methods Chronic second grade hepatitis merge early the time liver cirrhosis patient 81 examples stochastically divide into the treatment group (40 examples) and Comparison group (41 examples). Governs Cures the group to give the soft liver chemical fiber pill treatment; Comparison group with the turtle armor soft liver piece, the advantage adds (the milk thistle prosperously Element capsule), treatment course 3 months. Around observation treatment liver function (ALT, AST, ALB, TBiL) With liver fibrosis (HA, IV-C, LN) and so on target change situation. Results After finally the treatment course had ended, the treatment group trouble spleen is big, the portal vein increases the width, the liver fibrosis target obvious change for the better, has the significance with Comparison group the comparison difference (P<0.05 or P<0.01). Conclusion The soft liver chemical fiber pill treatment chronic hepatitis B merge early time liver cirrhosis curative effect surpasses the turtle armor soft liver piece, the advantage adds prosperously.
    【Key words】The hepatitis B Liver fibrosis Early time liver cirrhosis Soft liver chemical fiber pill Turtle armor soft liver piece The advantage add prosperously
    中图分类号:R575 文献标识码:B 文章编号:1726-619X(2006)12-0007-02

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【参考文献】

[1] 肝纤维化中西医结合诊疗指南、中国中西医结合学会肝病专业委员会.中西医结合肝病杂志,2006,5:316~320
[2] 中华医学会传染病与寄生虫学分会、肝病学分会.病毒性肝炎
[3] 粱扩寰,李绍白,主编.肝脏病学.人民卫生出版社,2003.12
[4] 权启镇,孙自勤,王要军,主编.新肝脏病学.山东科技出版社,2002
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